Unrelated Donor Transplant
What is Unrelated Donor Transplant?
- Finding a match within the family can be difficult sometimes. As many as 30 percent do not find a match within the family,in case of patients needing stem cells from a donor.
- However, the remaining 70 percent can find a good match outside the immediate family through donor registries.
- To improve chances of finding matches for everyone, it is imperative that registries include donors from as many ethnic groups as possible.
How is an unrelated donor identified?
- Volunteer unrelated donors are usually registered in large national registries.
- The age, gender and partial or complete HLA typing can help identify the right candidate.
- The transplant centre selects the best matched unrelated donor after several rounds of HLA testing.
- The donor is tested at the nearest donor center and after consenting undergoes either a marrow harvest or G-CSF (granulocyte colony-stimulating factor) mobilized peripheral blood collection.